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Aspirin Targeted As Colon Cancer Prevention

A recent study has made headlines in the medical world when aspirin was linked to the possible prevention of colon cancer. Previous research in this matter has given the indication that following a colorectal cancer diagnosis aspirin improves chances of survival, but this information doesn’t come with a guarantee, and like many other preventative cancer treatments, the results will vary by person as well as type and stage of cancer.

Playing A Role

Even with all of the research and testing underway there’s no complete understanding of what role it is that aspirin plays in the cancer prevention, but it seems to be working for some patients and that’s better than other treatments on the market. Live Science suggests: “For now, they speculate that aspirin may affect the ability of tumor cells circulating in the body to develop into new cancer growths, or metastases.”

The benefit seems to happen under direction of a low dosage after diagnosis of colon cancer with antigen-positive tumors in the category of HLA class I. Patients who had lost the HLA class I tumor found that the addition of aspirin to their daily treatments did nothing in regards to slowing the disease. It has been suggested that the circulation of aspirin surrounding tumor and metastatic deposit development is what allows this drug to make such a big difference.

The Test

The most recent study on this subject reviewed tissue samples from nearly one thousand patients who were already diagnosed with colon cancer, and who had completed the surgical procedure to remedy it within the time rage of 2002 to 2008. The samples varied, but included HLA class 1 antigen, as well as PTGS2 (prostaglandin endoperoxide synthase 2. The use of the aspirin was as prescribed by patient’s oncology team and information was taken from a database of prescriptions. 18.2 percent of the users took the aspirin, and of that 18.2 percent, there was a death rate of 37.9 percent. This is an incredible difference from the 48.5 percent death rate among the nonusers. Authors suggest the results are likely the effect of aspirin on circulating tumor cells and their ability to develop into metastatic deposits.

Other Cancer News

Colon cancer might be the big news lately in relation to the many studies on aspirin’s effect on the diseases, but it isn’t the only type of cancer that seems to benefit from taking one of these tablets every day. Aspirin has also been suggested to help decrease the odds of ovarian cancer being developed in women. Exactsciences.com writes: “Most recently, a study published in the Journal of the National Cancer Institute showed women who take a small dose of aspirin had up to 20% decreased risk of developing ovarian cancer, again reigniting the discussion around aspirin's cancer-fighting potential.”

Obviously all of these hopeful uses for aspirin need to be cleared with your attending physician, especially if you’ve already been diagnosed with something and are taking the required medication to treat it. Although aspirin is a mild pain reliever, when mixed with other drugs, the effects can be completely different than when taken on its own.

Doctors and scientists are still working on cures and preventative methods of treating different cancers, and as of now there isn’t a definitive proven method of practice to keep you safe, whether it’s colon, ovarian, or any other type of cancer. Aspirin is being viewed as a possible prevention tool, and it’s fine to be hopeful, not don’t lose sight of your prescribed treatments and follow-ups with your attending physician. Each part of the cancer therapy is important for different reasons and your doctor is the only person who will know which suit you best.

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